formulation design and optimization of direct compressed tablets of cefuroxime axetil using experimental design
نویسندگان
چکیده
منابع مشابه
Floating Matrix Tablets of Domperidone Formulation and Optimization Using Simplex Lattice Design
The purpose of this research was to prepare a floating matrix tablet containing domperidone as a model drug. Polyethylene oxide (PEO) and hydroxypropyl methylcellulose (HPMC) were evaluated for matrix-forming properties. A simplex lattice design was applied to systemically optimize the drug release profile. The amounts of PEO WSR 303, HPMC K15M and sodium bicarbonate were selected as independen...
متن کاملFormulation Optimization and Assessment of Dexamethasone Orally Disintegrating Tablets Using Box-Behnken Design
The aim of this study was to prepare orally disintegrating tablets (ODTs) containingdexamethasone (DEX) by direct compression method with sufficient hardness and rapiddisintegration time. In order to save time, money, and human resources in designing andimprovement of formulation, the statistical software Design Expert is used. Box–Behnkenresponse surface methodology was applied to evaluate and...
متن کاملFloating Matrix Tablets of Domperidone Formulation and Optimization Using Simplex Lattice Design
The purpose of this research was to prepare a floating matrix tablet containing domperidone as a model drug. Polyethylene oxide (PEO) and hydroxypropyl methylcellulose (HPMC) were evaluated for matrix-forming properties. A simplex lattice design was applied to systemically optimize the drug release profile. The amounts of PEO WSR 303, HPMC K15M and sodium bicarbonate were selected as independen...
متن کاملFormulation Optimization and Assessment of Dexamethasone Orally Disintegrating Tablets Using Box-Behnken Design
The aim of this study was to prepare orally disintegrating tablets (ODTs) containingdexamethasone (DEX) by direct compression method with sufficient hardness and rapiddisintegration time. In order to save time, money, and human resources in designing andimprovement of formulation, the statistical software Design Expert is used. Box–Behnkenresponse surface methodology was applied to evaluate and...
متن کاملThe stability of Cefuroxime axetil in tablets.
The stability of cefuroxime axetil in BIORACEF tablets was studied by means of long term (298 K/60% RH), intermediate (303 K/65% RH), accelerated (313 K/75% RH) and stress stability tests. Changes in the concentration of cefuroxime axetil diastereoisomers A and B and their total was determined using the RP-HPLC method, as described in a monograph of Cefuroxime axetil tablets in the British Phar...
متن کاملOptimization of a Waterborne Epoxy Coatings Formulation via Experimental Design
Waterborne Epoxy based coatings were prepared by using a water-borne epoxy resin and a suitable hardener. The formulation and optimization procedure were carried out on the bases of experimental designs by the mixture design technique in which the important paint properties are modeled by using special cubic model. The corrosion behavior of these coatings was investigated using electrochemical ...
متن کاملمنابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
عنوان ژورنال:
research in pharmaceutical sciencesجلد ۷، شماره ۵، صفحات ۰-۰
میزبانی شده توسط پلتفرم ابری doprax.com
copyright © 2015-2023